Articles

The need for a European hepatitis C programme monitoring resistance to direct-acting antiviral agents in real life to eliminate hepatitis C

HIV-1 Infection in Cyprus, the Eastern Mediterranean European Frontier: A Densley Sampled Transmission Dynamics Analysis from 1986 to 2012

Letter to the editor: Pre-exposure prophylaxis for HIV in Europe: The need for resistance surveillance
C van Tienen, D van de Vijver, T Noori, A Sönnerborg, C Boucher 
 Eurosurveillance, Volume 22, Issue 11, 16 March 2017

HIV-1 transmission between MSM and heterosexuals, and increasing proportions of circulating recombinant forms in the Nordic Countries.
Esbjörnsson,J., Mild, M., Audelin, A., Fonager, J., Skar,H., Bruun Jørgensen,L., Liitsola,K., Björkman,P., Bratt,G., Gisslén, M., Sönnerborg,A., Nielsen,C., Medstrand,P., Albert,J.
Virus Evolution: 27 April 2016

The global spread of HIV-1 subtype B epidemic
Magiorkinis, G., Angelis, K., Mamais, I Katzourakis, A., Hatzakis, A., Albert, J., Lawyer, G., Hamouda, Struck, D., Vercauteren, J., Wensing, A., Alexiev, I., Åsjö, B., Balotta, G., Gomes, P., Camacho, R., Coughlan, S., Griskevicius, A., Grossman, Z., Horban, A.,  Kostrikis,L., Zidovec Lepej, S., Liitsola, K., Linka, M., Nielsen, C., Otelea, D.,  Paredes, R., Poljak, P., Elizabeth, Puchhammer-Stöckl, E., Schmit, J.C., Sönnerborg, A., Staneková, D., Stanojevic, M., Boucher C.A.B., on behalf of the SPREAD program,Nikolopoulos, G., Vasylyeva, T., Friedman, S.R., Van de Vijver, D., Angarano, G.,  Chaix, M., De Luca, A., Korn, K., Loveday, C., Soriano, V., Yerly, S., Zazzi,M., Vandamme, AM, ParaskevisD.
Infect Genet Evol. 2016 Jun 2. pii: S1567-1348(16)30223-4.

Transmission of HIV drug resistance and the predicted effect on current first-line regimens in Europe.
Hofstra LM, Sauvageot N, Albert J, Alexiev I, Garcia F, Struck D, Van de Vijver DA, Åsjö B, Beshkov D, Coughlan S, Descamps D, Griskevicius A, Hamouda O, Horban A, Van Kasteren M, Kolupajeva T, Kostrikis LG, Liitsola K, Linka M, Mor O, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Staneková D, Stanojevic M, Van Laethem K, Zazzi M, Lepej SZ, Boucher CA, Schmit JC, Wensing AM; SPREAD program.
Clin Infect Dis. 2016 Mar 1;62(5):655-63. 

A Population-Structured HIV Epidemic in Israel: Roles of Risk and Ethnicity.
Grossman Z, Avidor B, Mor Z, Chowers M, Levy I, Shahar E, Riesenberg K, Sthoeger Z, Maayan S, Shao W, Lorber M, Olstein-Pops K, Elbirt D, Elinav H, Asher I, Averbuch D, Istomin V, Gottesman BS, Kedem E, Girshengorn S, Kra-Oz Z, Shemer Avni Y, Radian Sade S, Turner D, Maldarelli F.
PLoS One. 2015 Aug 24;10(8):e0135061. doi: 10.1371/journal.pone.0135061. eCollection 2015.

Primary resistance to integrase strand-transfer inhibitors in Europe.
Casadellà M, van Ham PM, Noguera-Julian M, van Kessel A, Pou C, Hofstra LM, Santos JR, Garcia F, Struck D, Alexiev I, Bakken Kran AM, Hoepelman AI, Kostrikis LG, Somogyi S, Liitsola K, Linka M, Nielsen C, Otelea D, Paraskevis D, Poljak M, Puchhammer-Stöckl E, Staneková D, Stanojevic M, Van Laethem K, Zidovec Lepej S, Clotet B, Boucher CA, Paredes R, Wensing AM; SPREAD programme.
Journal of Antimicrobiology Chemotherapy 2015 Jul 17. pii: dkv202. [Epub ahead of print]

Combined Analysis of the Prevalence of drug Resistant HBV in antiviral therapy Experienced patients in Europe (CAPRE).
Hermans LE, Svicher V, Pas SD, Salpini R, Alvarez M, Ben Ari Z, Boland G, Bruzzone B, Coppola N, Seguin-Devaux C, Dyda T, Garcia F, Kaiser R, Köse S, Krarup H, Lazarevic I, Lunar MM, Maylin S, Micheli V, Mor O, Paraschiv S, Paraskevis D, Poljak M, Puchhammer-Stöckl E, Simon F, Stanojevic M, Stene-Johansen K, Tihic N, Trimoulet P, Verheyen J, Vince A, Weis N, Yalcinkaya T, Zidovec Lepej S, Perno C, Boucher CA, Wensing AM; HEPVIR working group of the European Society for translational antiviral research (ESAR).
J Infect Dis. (2015) doi: 10.1093/infdis/jiv363

Efficacy of tenofovir and efavirenz in combination with lamivudine or emtricitabine in antiretroviral-naive patients
Swartz JE, Vandekerckhove L, Ammerlaan H, de Vries AC, Begovac J, Bierman WF, Boucher CA, van der Ende ME, Grossman Z, Kaiser R, Levy I, Mudrikova T, Paredes R, Perez-Bercoff D, Pronk M, Richter C, Schmit JC, Vercauteren J, Zazzi M, Židovec Lepej S, De Luca A, Wensing AM; on behalf of the European Society for translational Antiviral Research (ESAR). Efficacy of tenofovir and efavirenz in combination with lamivudine or emtricitabine in antiretroviral-naive patients.
European Journal of Antimicrobiological Chemotherapy 2015 Mar 3. pii: dkv033. [Epub ahead of print] PubMed PMID: 25740950.

Low HIV-1 transmitted drug resistance in Bulgaria against a background of high clade diversity
Ivailo Alexiev, Anupama Shankar, A. M. J. Wensing, Danail Beshkov, Ivaylo Elenkov, Mariyana Stoycheva, Daniela Nikolova, Maria Nikolova, and William M. Switzer
Journal of Antimicrobial Chemotherapy 2015 February 3, 2015 doi:10.1093/jac/dkv011


2014
Distribution of HIV-1 subtypes circulating in Slovakia (2009-2012)
Chabadová Z, Habeková M, Truska P, Drobková T, Mojzesová M, Staneková D.
Acta Virologia 2014 Dec;58(4):317-24.

Global dispersal pattern of HIV-1 CRF01_AE: A genetic trace of human mobility related to heterosexual activities centralized in South-East Asia.
Angelis K, Albert J, Mamais I, Magiorkinis G, Hatzakis A, Hamouda O, Struck D, Vercauteren J, Wensing AM, Alexiev I, Asjö B, Balotta C, Camacho RJ, Coughlan S, Griskevicius A, Grossman Z, Horban A, Kostrikis LG, Lepej S, Liitsola K, Linka M, Nielsen C, Otelea D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Boucher CA, Kaplan L, Vandamme AM, Paraskevis D.
The Journal of Infectious Diseases 2014 Dec 15. pii: jiu666.

Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity.
Pingen M, Wensing AM, Fransen K, De Bel A, de Jong D, Hoepelman AI, Magiorkinis E, Paraskevis D, Lunar MM, Poljak M, Nijhuis M, Boucher CA; SPREAD programme.Retrovirology. 2014 Nov 29;11(1):105. doi: 10.1186/s12977-014-0105-9.

Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe
Dineke Frentz, David AMC Van de Vijver, Ana B Abecasis, Jan Albert, Osamah Hamouda, Louise B Jørgensen, Claudia Kücherer, Daniel Struck, Jean-Claude Schmit, Jurgen Vercauteren, Birgitta Åsjö, Claudia Balotta, Danail Beshkov, Ricardo J Camacho, Bonaventura Clotet, Suzie Coughlan, Algirdas Griskevicius, Zehava Grossman, Andrzej Horban, Tatjana Kolupajeva, Klaus Korn, Leondios G Kostrikis, Kirsi Liitsola, Marek Linka, Claus Nielsen, Dan Otelea, Dimitrios Paraskevis, Roger Paredes, Mario Poljak, Elisabeth Puchhammer-Stöckl, Anders Sönnerborg, Danica Stanekova, Maja Stanojevic, Eric Van Wijngaerden, Annemarie MJ Wensing and Charles AB Boucher.
BMC Infect Dis. 2014 Jul 21;14(1):407.

Trends and Predictors of Transmitted Drug Resistance (TDR) and Clusters with TDR in a Local Belgian HIV-1 Epidemic.
Pineda-Peña AC, Schrooten Y, Vinken L, Ferreira F, Li G, Trovão NS, Khouri R, Derdelinckx I, De Munter P, Kücherer C, Kostrikis LG, Nielsen C, Littsola K, Wensing A, Stanojevic M, Paredes R, Balotta C, Albert J, Boucher C, Gomez-Lopez A, Van Wijngaerden E, Van Ranst M, Vercauteren J, Vandamme AM, Van Laethem K.
PLoS One. 2014 Jul 8;9(7):e101738. doi: 10.1371/journal.pone.0101738. eCollection 2014.

Patterns of transmitted HIV drug resistance in Europe vary by risk group.
Frentz D, van de Vijver D, Abecasis A, Albert J, Hamouda O, Jørgensen L, Kücherer C, Struck D, Schmit JC, Vercauteren J, Asjö B, Balotta C, Bergin C, Beshkov D, Camacho R, Clotet B, Griskevicius A, Grossman Z, Horban A, Kolupajeva T, Korn K, Kostrikis L, Linka KL, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Stanekova D, Stanojevic M, Vandamme AM, Boucher C, Wensing A; SPREAD Programme.
PLoS One. 2014 Apr 10;9(4):e94495. doi: 10.1371/journal.pone.0094495. eCollection 2014.

Transmitted drug resistance to rilpivirine among antiretroviral-naïve patients living with HIV from northern Poland
Parczewski M, Urbańska A, Maciejewska K, Witak-Jȩdra M, Leszczyszyn-Pynka M.
J Int AIDS Soc. 2014 Apr 17;17(1):18929. doi: 10.7448/IAS.17.1.18929.

Comparative performances of HIV-1 RNA load assays at low viral load levels: results of an international collaboration.
Swenson LC, Cobb B, Geretti AM, Harrigan PR, Poljak M, Seguin-Devaux C, Verhofstede C, Wirden M, Amendola A, Boni J, Bourlet T, Huder JB, Karasi JC, Zidovec Lepej S, Lunar MM, Mukabayire O, Schuurman R, Tomazic J, Van Laethem K, Vandekerckhove L, Wensing AM; International Viral Load Assay Collaboration.
J Clin Microbiol. 2014 Feb;52(2):517-23. doi: 10.1128/JCM.02461-13. Epub 2013 Dec 4

Limited cross-border infections in patients newly diagnosed with HIV in Europe
Frentz D, Wensing AM, Albert J, Paraskevis D, Abecasis AB, Hamouda O, Jørgensen LB, Kücherer C, Struck D, Schmit JC, Asjö B, Balotta C, Beshkov D, Camacho RJ, Clotet B, Coughlan S, De Wit S, Griskevicius A, Grossman Z, Horban A, Kolupajeva T, Korn K, Kostrikis LG, Liitsola K, Linka M, Nielsen C, Otelea D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Stanekova D, Stanojevic M, Vandamme AM, Boucher CA, Van de Vijver DA; SPREAD Programme.
Retrovirology. 2013 Apr 3;10:36. doi: 10.1186/1742-4690-10-36

Detailed Molecular Epidemiologic Characterization of HIV-1 Infection in Bulgaria Reveals Broad Diversity and Evolving Phylodynamics
Ivailo Alexiev Ivanov, Danail Beshkov, Anupama Shankar, Debra L. Hanson, Dimitrios Paraskevis, Viara Georgieva, Lyudmila Karamacheva, Hristo Taskov, Tonka Varleva, Ivaylo Elenkov, Mariana Stoicheva, Daniela Nikolova, William M. Switzer
PLoS One. 2013;8(3):e59666. doi: 10.1371/journal.pone.0059666. Epub 2013 Mar 19.

Transmission patterns of HIV-subtypes A/AE versus B: inferring risk-behavior trends and treatment-efficacy limitations from viral genotypic data obtained prior to and during antiretroviral therapy.
Avidor B, Turner D, Mor Z, Chalom S, Riesenberg K, Shahar E, Pollack S, Elbirt D, Sthoeger Z, Maayan S, Olshtain-Pops K, Averbuch D, Chowers M, Istomin V, Anis E, Mendelson E, Ram D, Levy I, Grossman Z.
PLoS One. 2013;8(3):e57789. doi: 10.1371/journal.pone.0057789. Epub 2013 Mar 1.

HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics
Abecasis AB, Wensing AM, Paraskevis D, Vercauteren J, Theys K, Van de Vijver DA, Albert J, Asjö B, Balotta C, Beshkov D, Camacho RJ, Clotet B, De Gascun C, Griskevicius A, Grossman Z, Hamouda O, Horban A, Kolupajeva T, Korn K, Kostrikis LG, Kücherer C, Liitsola K, Linka M, Nielsen C, Otelea D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Stanekova D, Stanojevic M, Struck D, Boucher CA, Vandamme AM on behalf of the SPREAD programme.
Retrovirology. 2013 Jan 14;10:7. doi: 10.1186/1742-4690-10-7

The prevalence of transmitted drug resistance in newly-diagnosed HIV-infected individuals in Croatia: the role of transmission clusters of men who have sex with men carring T215S surveillance drug resistance mutation.
Grgic I, Zidovec Lepej S, Lunar M, Poljak M, Vince A, Baca Vrakela I, Planinic A, Seme K, Begovac
J. AIDS Res Hum Retroviruses. 2013 Feb;29(2):329-36. doi: 10.1089/AID.2012.0191.

Prevalence of HIV Type 1 Transmitted Drug Resistance in Slovenia: 2005-2010.
Lunar MM, Zidovec Lepej S, Abecasis AB, Tomažič J, Vidmar L, Karner P, Vovko TD, Pečavar B, Maver PJ, Seme K, Poljak M.
AIDS Res Hum Retroviruses. 2013 Feb;29(2):343-9. doi: 10.1089/AID.2012.0152. Epub 2012 Aug 29.

Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients
Kristof Theys, Koen Deforche, Jurgen Vercauteren, Pieter Libin, David A.M.C. van de Vijver, Jan Albert, Birgitta Asjo, Claudia Balotta, Marie Bruckova, Ricardo J. Camacho, Bonaventura Clotet, Suzie Coughlan, Zehava Grossman, Osamah Hamouda, Andrzei Horban, Klaus Korn, Leondios G. Kostrikis, Claudia Kucherer, Claus Nielsen, Dimitrios Paraskevis, Mario Poljak, Elisabeth Puchhammer-Stockl, Chiara Riva, Lidia Ruiz, Kirsi Liitsola, Jean-Claude Schmit, Rob Schuurman, Anders Sonnerborg, Danica Stanekova, Maja Stanojevic, Daniel Struck, Kristel van Laethem, Annemarie M.J. Wensing, Charles A.B. Boucher and Anne-Mieke Vandamme
Retrovirology. 2012 Oct 3;9:81. doi: 10.1186/1742-4690-9-81.

Prevalence of HIV and sexually transmitted infections and patterns of recent HIV testing among men who have sex with men in Zagreb, Croatia.
Bozicevic I, Lepej SZ, Rode OD, Grgic I, Jankovic P, Dominkovic Z, Lukas D, Johnston LG, Begovac J.
Sex Transm Infect. 2012 Nov;88(7):539-44. doi: 10.1136/sextrans-2011-050374. Epub 2012 May 24.

HIV1 molecular epidemiology in the Balkans: a melting pot for high genetic diversity.
Stanojevic M, Alexiev I, Beshkov D, Gökengin D, Mezei M, Minarovits J, Otelea D, Paraschiv S, Poljak M, Zidovec-Lepej S, Paraskevis D.
AIDS Rev. 2012 Jan-Mar;14(1):28-36. Review.

Molecular typing of the recently expanding subtype B HIV-1 epidemic in Romania: Evidence for local spread among MSMs in Bucharest area.
Paraschiv S, Otelea D, Batan I, Baicus C, Magiorkinis G, Paraskevis D.
Infect Genet Evol. 2012 Jul;12(5):1052-7. Epub 2012 Mar 10.

Low Prevalence of Transmitted Drug Resistance in Patients Newly Diagnosed with HIV-1 Infection in Sweden 2003-2010.
Karlsson A, Björkman P, Bratt G, Ekvall H, Gisslén M, Sönnerborg A, Mild M, Albert J.
PLoS One. 2012;7(3):e33484. Epub 2012 Mar 20.

European guidelines on the clinical management of HIV-1 tropism testing.
Vandekerckhove L, Wensing A, Kaiser R, Brun-Vézinet F, Clotet B, De Luca A, Dressler S, Garcia F, Geretti A, Klimkait T, Korn K, Masquelier B, Perno C, Schapiro J, Soriano V, Sönnerborg A, Vandamme AM, Verhofstede C, Walter H, Zazzi M, Boucher C; on behalf of the European Consensus Group on clinical management of tropism testing.
Lancet Infect Dis. 2011 May;11(5):394-407. Epub 2011 Mar 21.

Evolutionary pathways of transmitted drug-resistant HIV-1.
Pingen M, Nijhuis M, de Bruijn JA, Boucher CA, Wensing AM.
J Antimicrob Chemother. 2011 Apr 18. Epub 2011 Apr 18

Men who have sex with men, risk behavior, and HIV infection: integrative analysis of clinical, epidemiological, and laboratory databases.
Levy I, Mor Z, Anis E, Maayan S, Leshem E, Pollack S, Chowers M, Mor O, Riesenberg K, Sthoeger Z, Ram D, Grossman Z.
Clin Infect Dis. 2011 Jun;52(11):1363-70.